Chemotherapy drugs or named regimens currently linked to Breast Cancer in the Chemo database are listed alphabetically. Actual use depends on stage, tumor biology, biomarkers, prior treatment, organ function, performance status, and the treating oncology team.
AC
Short Description
AC is a chemotherapy combination regimen. AC is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: doxorubicin and cyclophosphamide. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Breast cancer regimen used in adjuvant, neoadjuvant, or advanced settings. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/ac
AC-T
Short Description
AC-T is a chemotherapy combination regimen. AC-T is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: doxorubicin and cyclophosphamide followed by paclitaxel or docetaxel. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Breast cancer sequential anthracycline/taxane regimen. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/ac-t
CAF
Short Description
CAF is a chemotherapy combination regimen. CAF is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: cyclophosphamide, doxorubicin, and fluorouracil. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Older or less commonly used; current role may be limited by newer regimens, toxicity, biomarkers, or supportive-care standards.
Older breast cancer chemotherapy regimen. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/caf
Capecitabine
Short Description
Capecitabine is a oral fluoropyrimidine antimetabolite prodrug used as anticancer chemotherapy. Capecitabine is an anticancer chemotherapy or oncology drug option. It is recorded as oral fluoropyrimidine antimetabolite prodrug. Typical application: Oral tablets. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Oral fluoropyrimidine used in breast and GI cancers and as a substitute for infusional fluorouracil in some regimens. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
Carboplatin
Short Description
Carboplatin is a platinum compound used as anticancer chemotherapy. Carboplatin is an anticancer chemotherapy or oncology drug option. It is recorded as platinum compound. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Common platinum option across ovarian, lung, gynecologic, head and neck, pediatric, and other cancer regimens. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
CMF
Short Description
CMF is a chemotherapy combination regimen. CMF is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: cyclophosphamide, methotrexate, and fluorouracil. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Older or less commonly used; current role may be limited by newer regimens, toxicity, biomarkers, or supportive-care standards.
Older breast cancer regimen retained for historical and selected-use reference. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cmf
Cyclophosphamide
Short Description
Cyclophosphamide is a alkylating agent used as anticancer chemotherapy. Cyclophosphamide is an anticancer chemotherapy or oncology drug option. It is recorded as alkylating agent. Typical application: IV or oral. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Very common cytotoxic drug used in breast, lymphoma, leukemia, sarcoma, pediatric, and transplant regimens. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Docetaxel
Short Description
Docetaxel is a taxane microtubule inhibitor used as anticancer chemotherapy. Docetaxel is an anticancer chemotherapy or oncology drug option. It is recorded as taxane microtubule inhibitor. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Taxane used across breast, prostate, lung, gastric, head and neck, and other solid tumors. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Dose-Dense AC-T
Short Description
Dose-Dense AC-T is a chemotherapy combination regimen. Dose-Dense AC-T is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: dose-dense doxorubicin/cyclophosphamide followed by taxane therapy. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Breast cancer regimen using shorter cycle intervals with growth-factor support. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/types/breast/treatment/chemotherapy
Doxorubicin
Short Description
Doxorubicin is a anthracycline antitumor antibiotic used as anticancer chemotherapy. Doxorubicin is an anticancer chemotherapy or oncology drug option. It is recorded as anthracycline antitumor antibiotic. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Widely used anthracycline in breast cancer, lymphomas, sarcomas, and selected other cancers. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Doxorubicin Liposome
Short Description
Doxorubicin Liposome is a liposomal anthracycline formulation used as anticancer chemotherapy. Doxorubicin Liposome is cataloged here as an individual chemotherapy drug. It may be used alone or as part of combination regimens depending on cancer type, stage, biomarkers, prior treatment, organ function, and treatment goal.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Liposomal form used in recurrent ovarian cancer, Kaposi sarcoma, breast cancer, myeloma combinations, and selected sarcoma contexts. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
EC
Short Description
EC is a chemotherapy combination regimen. EC is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: epirubicin and cyclophosphamide. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Breast cancer anthracycline regimen. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
Epirubicin
Short Description
Epirubicin is a anthracycline antitumor antibiotic used as anticancer chemotherapy. Epirubicin is an anticancer chemotherapy or oncology drug option. It is recorded as anthracycline antitumor antibiotic. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Used in breast cancer and historical upper-GI regimens such as ECF/ECX. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Eribulin
Short Description
Eribulin is a microtubule dynamics inhibitor used as anticancer chemotherapy. Eribulin is an anticancer chemotherapy or oncology drug option. It is recorded as microtubule dynamics inhibitor. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Used in metastatic breast cancer and liposarcoma/soft-tissue sarcoma settings. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
FAC
Short Description
FAC is a chemotherapy combination regimen. FAC is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: fluorouracil, doxorubicin, and cyclophosphamide. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Older or less commonly used; current role may be limited by newer regimens, toxicity, biomarkers, or supportive-care standards.
Older breast cancer regimen closely related to CAF. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
FEC
Short Description
FEC is a chemotherapy combination regimen. FEC is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: fluorouracil, epirubicin, and cyclophosphamide. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Anthracycline-based breast cancer regimen. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
Fluorouracil
Short Description
Fluorouracil is a fluoropyrimidine antimetabolite used as anticancer chemotherapy. Fluorouracil is an anticancer chemotherapy or oncology drug option. It is recorded as fluoropyrimidine antimetabolite. Typical application: IV infusion or bolus. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Core chemotherapy drug for colorectal, anal, breast, upper GI, pancreatic, biliary, and head and neck cancers. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Gemcitabine
Short Description
Gemcitabine is a nucleoside analog antimetabolite used as anticancer chemotherapy. Gemcitabine is an anticancer chemotherapy or oncology drug option. It is recorded as nucleoside analog antimetabolite. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Used in pancreatic, biliary, bladder, lung, breast, ovarian, mesothelioma, and sarcoma regimens. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
Ixabepilone
Short Description
Ixabepilone is a epothilone microtubule inhibitor used as anticancer chemotherapy. Ixabepilone is an anticancer chemotherapy or oncology drug option. It is recorded as epothilone microtubule inhibitor. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Used in metastatic or locally advanced breast cancer after prior therapies. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Methotrexate
Short Description
Methotrexate is a antifolate antimetabolite used as anticancer chemotherapy. Methotrexate is an anticancer chemotherapy or oncology drug option. It is recorded as antifolate antimetabolite. Typical application: Oral, IV, IM, or intrathecal. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Used in leukemia, lymphoma, CNS lymphoma, osteosarcoma, gestational trophoblastic disease, and older breast/head-neck/bladder contexts. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Mitomycin
Short Description
Mitomycin is a antitumor antibiotic / bioreductive alkylating agent used as anticancer chemotherapy. Mitomycin is cataloged here as an individual chemotherapy drug. It may be used alone or as part of combination regimens depending on cancer type, stage, biomarkers, prior treatment, organ function, and treatment goal.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Used with fluoropyrimidines in anal cancer and intravesically in bladder cancer; older GI/breast/head-neck uses retained. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Mitoxantrone
Short Description
Mitoxantrone is a anthracenedione/topoisomerase II inhibitor used as anticancer chemotherapy. Mitoxantrone is an anticancer chemotherapy or oncology drug option. It is recorded as anthracenedione/topoisomerase II inhibitor. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Older or less commonly used; current role may be limited by newer regimens, toxicity, biomarkers, or supportive-care standards.
Older chemotherapy used in AML, lymphoma, breast cancer, and prostate cancer palliation. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Paclitaxel
Short Description
Paclitaxel is a taxane microtubule inhibitor used as anticancer chemotherapy. Paclitaxel is an anticancer chemotherapy or oncology drug option. It is recorded as taxane microtubule inhibitor. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Common taxane used across breast, ovarian, lung, gynecologic, upper GI, head and neck, bladder, and Kaposi sarcoma settings. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Paclitaxel Albumin-stabilized Nanoparticle Formulation
Short Description
Paclitaxel Albumin-stabilized Nanoparticle Formulation is a albumin-bound taxane microtubule inhibitor used as anticancer chemotherapy. Paclitaxel Albumin-stabilized Nanoparticle Formulation is cataloged here as an individual chemotherapy drug. It may be used alone or as part of combination regimens depending on cancer type, stage, biomarkers, prior treatment, organ function, and treatment goal.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Also known as nab-paclitaxel; used in breast, pancreatic, lung, and ovarian cancer contexts. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
TAC
Short Description
TAC is a chemotherapy combination regimen. TAC is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: docetaxel, doxorubicin, and cyclophosphamide. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Breast cancer taxane/anthracycline regimen. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
TC
Short Description
TC is a chemotherapy combination regimen. TC is an anticancer chemotherapy or oncology drug option. It is recorded as Combination regimen: docetaxel and cyclophosphamide. Typical application: Combination regimen; route and cycle schedule depend on protocol.. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Breast cancer non-anthracycline regimen. Specific use depends on diagnosis, stage, fitness, prior therapy, and current guideline status.
Sourcehttps://www.cancer.gov/types/breast/treatment/chemotherapy
Thiotepa
Short Description
Thiotepa is a alkylating agent used as anticancer chemotherapy. Thiotepa is an anticancer chemotherapy or oncology drug option. It is recorded as alkylating agent. Typical application: IV, intravesical, or transplant conditioning. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Older or less commonly used; current role may be limited by newer regimens, toxicity, biomarkers, or supportive-care standards.
Older cytotoxic agent and conditioning drug; intravesical and high-dose uses retained. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.gov/about-cancer/treatment/drugs/cancer-drugs
Vinblastine
Short Description
Vinblastine is a vinca alkaloid microtubule inhibitor used as anticancer chemotherapy. Vinblastine is an anticancer chemotherapy or oncology drug option. It is recorded as vinca alkaloid microtubule inhibitor. Typical application: IV infusion. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Classic component of ABVD and older use in germ-cell tumors, Kaposi sarcoma, breast cancer, and CTCL. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html
Vinorelbine
Short Description
Vinorelbine is a vinca alkaloid microtubule inhibitor used as anticancer chemotherapy. Vinorelbine is an anticancer chemotherapy or oncology drug option. It is recorded as vinca alkaloid microtubule inhibitor. Typical application: IV infusion or oral in some regions. Review cancer indication, treatment line, expected benefit, side effects, interactions, monitoring needs, and fit with the patient?s oncology plan.
Effectiveness
Recognized chemotherapy option or regimen family; effectiveness depends on stage, biology, prior therapy, and patient fitness.
Used in NSCLC and metastatic breast cancer settings. Use varies by disease setting and should be checked against current oncology guidelines.
Sourcehttps://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/types-of-chemo-drugs.html